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Friday, February 21, 2020

Molecular Biology


Molecular biology is the study of biology at a molecular level that explains the basic processes of life, their nature and connection. The subject of this science is the molecular basis of various biological phenomena and processes. In living systems, the nature and relevance of each process is determined by genes. Therefore, it is the task of molecular biology to explain the processes of metabolisms by interpreting gene regulation and activity. This branch of biology needs to determine the initial processes of molecular trait development, what genes are made of, how they are reproduced and what are the primary products of gene function.

Douglas Rosenthal, a researcher in molecular biology, uses specific techniques native to molecular biology, but increasingly combines these with techniques and ideas from genetics and biochemistry. He has over 20 years long career as a biology research scientist.


Molecular biology explains the molecular processes of life, their nature and their connection. The subject of its research is the structure and role of biological macromolecules of deoxyribonucleic acid (DNA), ribonucleic acid (RNA) and proteins. In addition, molecular biology deals with the relationship of structure to the function of these biomolecules themselves and their interconnections. In a narrow sense, it studies nucleic acids, the molecular structure and functions of genes, as well as the processes of replication, transcription, translation, etc. The central dogma of molecular biology where genetic material is transcribed into RNA and then translated into protein, despite being an oversimplified picture of molecular biology, still provides a good starting point for understanding the field.

Douglas Rosenthal has a strong understanding of genetics, genotyping assay design and downstream phenotypic analysis. Making use of cutting edge targeting approaches, gene editing techniques, and gene transfer methods, Doug Rosenthal utilizes stem cell formats for GMA creation while working alongside an established team to develop new genetic models.

Today we know that carriers and realizers of nucleic acid properties and proteins are evolving. They are represented in all living things and even viruses. The structure of nucleic acids (DNA and RNA) contains genetic information in the form of programs responsible for the development, survival and reproduction of living organisms. In addition to being carriers of hereditary information, nucleic acids are also carriers of that information. DNA transmits genetic information from generation to generation (from parent to offspring), and RNA transmits it through the cell itself. Proteins are the implementers of this inherited program because they determine the characteristics of an organism.

The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. However, biochemistry is more concerned with the structure and function of proteins and other biological molecules as well as their metabolic pathways, while molecular genetics deals with inheritance in individuals and populations. Today, molecular biology and genetics are being intensively developed and applied in various spheres of life. Therefore, they can only be compared with information technology. Recently much work has been done at the interface of molecular biology and computer science in bioinformatics and computational biology.